Across TCGA patient cohorts, PCBP2 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCBP2-associated genes across cancer lineages are ERK2, MEK1, and Myosin-IIa_pS1943. Each is linked with PCBP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCBP2-to-partner and partner-to-PCBP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCBP2→partner) and Y-score (partner→PCBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.245	+2.999	.006	.035	3	1
UCEC	MEK1 →	+0.356	+3.000	.036	.036	3	1
UCEC	Myosin-IIa_pS1943 →	+0.200	+3.713	.037	<.001	3	1
UCEC	N-Ras →	-0.145	-3.302	.009	.010	3	1
UCEC	XBP1 →	-0.236	-3.156	<.001	.018	3	1
UCEC	Caspase-7-cleavedD198 →	+1.240	+3.700	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

PCBP2 survival (RNA) · tumor vs normal (RNA) · all PCBP2 data types