PCBP1

Across TCGA patient cohorts, PCBP1 mutation is significantly associated with the RNA expression of many other genes, with 976 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCBP1-associated genes across cancer lineages are VN1R10P, SNORD116-23, and RNU6-1213P. Each is linked with PCBP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCBP1-to-partner and partner-to-PCBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VN1R10P grouped by PCBP1-low versus PCBP1-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCBP1→partner) and Y-score (partner→PCBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	VN1R10P →	+0.039	+4.878	<.001	.005	3	2
UCEC	SNORD116-23 →	+0.895	+2.847	<.001	<.001	3	2
UCEC	RNU6-1213P →	+0.325	+4.292	<.001	<.001	3	2
SKCM	RN7SL715P →	+0.123	+5.097	.007	.008	3	2
BLCA	MIR1238 →	+0.172	+4.007	<.001	.008	3	2
BLCA	SMARCE1P2 →	+0.105	+3.164	.004	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 976 associations by consensus.

VN1R10P by PCBP1 expression — LIHC

Explore this box plot interactively →