PCBP1

Across TCGA cell cohorts, PCBP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,109 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PCBP1-associated GO terms across cancer lineages are DNA strand elongation involved in DNA replication, Cell cycle DNA replication initiation, and Nuclear cell cycle DNA replication initiation. Each is linked with PCBP1 in more than 9 cancer types. Because this analysis shows association rather than direction, both PCBP1-to-partner and partner-to-PCBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA strand elongation involved in DNA replication grouped by PCBP1-low versus PCBP1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PCBP1→partner) and Y-score (partner→PCBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	DNA strand elongation involved in DNA replication →	+0.108	+0.800	<.001	<.001	3	10
OVARY	Cell cycle DNA replication initiation →	+0.151	+0.557	<.001	<.001	3	10
OVARY	Nuclear cell cycle DNA replication initiation →	+0.151	+0.557	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Mitotic DNA replication →	+0.167	+0.591	<.001	<.001	3	10
OVARY	Mitotic DNA replication initiation →	+0.151	+0.557	<.001	<.001	3	10
SOFT_TISSUE	Regulation of protein sumoylation →	+0.102	+0.658	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,109 associations by consensus.

DNA strand elongation involved in DNA replication by PCBP1 expression — BLOOD_Lymphoma

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