PCBD2

Across TCGA patient cohorts, PCBD2 protein abundance is significantly associated with the RNA expression of many other genes, with 11,067 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PCBD2-associated genes across cancer lineages are RAB23, MFAP2, and DESI2. Each is linked with PCBD2 in more than 4 cancer types. Because this analysis shows association rather than direction, both PCBD2-to-partner and partner-to-PCBD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCBD2 versus RAB23 in CCRCC, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCBD2→partner) and Y-score (partner→PCBD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	RAB23 →	-0.607	-0.311	<.001	<.001	3	5
OV	MFAP2 →	-1.265	-0.353	<.001	<.001	3	5
BRCA	DESI2 →	-0.671	-0.515	<.001	<.001	3	5
GBM	C4orf46 →	-0.666	-0.332	<.001	<.001	3	5
BRCA	GTSE1 →	-0.889	-0.362	<.001	<.001	3	5
GBM	FBXO5 →	-0.943	-0.347	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,067 associations by consensus.

PCBD2 vs RAB23 — CCRCC

Explore this scatter interactively →