PCBD2

Across TCGA cell cohorts, PCBD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,021 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PCBD2-associated GO terms across cancer lineages are Telomere maintenance via recombination, CAAX-box protein maturation, and Mitotic recombination. Each is linked with PCBD2 in more than 10 cancer types. Because this analysis shows association rather than direction, both PCBD2-to-partner and partner-to-PCBD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere maintenance via recombination grouped by PCBD2-low versus PCBD2-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PCBD2→partner) and Y-score (partner→PCBD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Telomere maintenance via recombination →	+0.103	+0.563	<.001	<.001	3	11
BREAST	CAAX-box protein maturation →	+0.122	+0.972	.003	.002	3	11
UPPER_AERODIGESTIVE_TRACT	Mitotic recombination →	+0.101	+0.838	.001	.003	3	10
BLOOD_Leukemia	Regulation of mitotic cytokinetic process →	+0.093	+0.450	.001	.001	2	11
BLOOD_Leukemia	Positive regulation of mitotic cytokinetic process →	+0.093	+0.450	.001	.001	2	11
BLOOD_Leukemia	Regulation of cytokinetic process →	+0.093	+0.450	.001	.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,021 associations by consensus.

Telomere maintenance via recombination by PCBD2 expression — BLOOD_Leukemia

Explore this box plot interactively →