PCBD1

Across TCGA patient cohorts, PCBD1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,264 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PCBD1-associated genes across cancer lineages are HMGN2P30, DMXL1, and CCNL2P1. Each is linked with PCBD1 in more than 3 cancer types. Because this analysis shows association rather than direction, both PCBD1-to-partner and partner-to-PCBD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCBD1 versus HMGN2P30 in PDAC, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCBD1→partner) and Y-score (partner→PCBD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	HMGN2P30 →	-0.782	-0.619	<.001	.001	3	4
BRCA	DMXL1 →	+0.817	+0.595	<.001	<.001	3	4
HNSC	CCNL2P1 →	+0.709	+0.945	<.001	<.001	3	4
BRCA	SLC40A1 →	+1.254	+0.381	<.001	.006	3	4
BRCA	ABCA8 →	+1.015	+0.766	.001	<.001	3	3
OV	GDI2P1 →	-0.447	-0.495	<.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,264 associations by consensus.

PCBD1 vs HMGN2P30 — PDAC

Explore this scatter interactively →