PCAT2

Across TCGA patient cohorts, PCAT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,736 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PCAT2-associated GO terms across cancer lineages are Maturation of SSU-rRNA, Positive regulation of establishment of protein localization to telomere, and Positive regulation of telomere maintenance. Each is linked with PCAT2 in more than 16 cancer types. Because this analysis shows association rather than direction, both PCAT2-to-partner and partner-to-PCAT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maturation of SSU-rRNA grouped by PCAT2-low versus PCAT2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PCAT2→partner) and Y-score (partner→PCAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Maturation of SSU-rRNA →	+0.057	+0.353	<.001	<.001	3	17
STAD	Positive regulation of establishment of protein localization to telomere →	+0.071	+0.427	<.001	<.001	3	16
STAD	Positive regulation of telomere maintenance →	+0.064	+0.375	<.001	<.001	3	16
STAD	Regulation of chromosome organization →	+0.065	+0.380	<.001	<.001	3	16
STAD	Positive regulation of chromosome organization →	+0.069	+0.381	<.001	<.001	3	16
STAD	Mitotic spindle organization →	+0.067	+0.353	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,736 associations by consensus.

Maturation of SSU-rRNA by PCAT2 expression — STAD

Explore this box plot interactively →