PCAT18

Across TCGA pan-cancer cohorts, PCAT18 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated PCAT18 data layer.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher PCAT18 RNA is associated with better overall survival. In most high-consensus cancer types, elevated PCAT18 expression acts as an unfavorable survival marker, although some lineages such as OV and BRCA show a favorable association.

OV, BRCA, and KIRP are the cancer types where PCAT18 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Tertile	All	0.890	0.785	<.001	102	view →
BRCA	OS	Tertile	All	0.635	0.517	<.001	86	view →
KIRP	OS	Tertile	All	0.984	0.884	<.001	43	view →
KIRC	DFS	Quartile	All	0.800	0.470	<.001	34	view →
HNSC	DFS	Tertile	III,IV	0.504	0.271	.006	32	view →
READ	DFS	Median	III,IV	0.564	0.857	.002	19	view →
ACC	DFS	Quartile	All	0.253	0.679	.003	19	view →
UVM	DFS	Quartile	II,III,IV	0.841	0.552	.022	14	view →
STAD	OS	Quartile	II,III,IV	0.289	0.546	.006	13	view →
PAAD	DFS	Quartile	II,III,IV	0.594	0.280	.005	12	view →
LUSC	OS	Median	IV	0.255	0.851	.021	12	view →
PRAD	DFS	Quartile	All	0.958	0.887	.024	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

PCAT18–OV (OS)

Open the OV breakdown →