PCAT1

Across TCGA pan-cancer cohorts, PCAT1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of PCAT1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where PCAT1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PCAT1 is over-expressed in tumor, although a few such as LUAD and THCA show the opposite, repressed pattern.

COAD, STAD, and READ are the cancer types where PCAT1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PCAT1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.303	<.001	9	view →
STAD	Male	II,III,IV	+0.501	<.001	7	view →
READ	All	II,III,IV	+0.380	<.001	7	view →
HNSC	All	All	+0.302	.001	7	view →
LUSC	Female	All	+0.761	<.001	6	view →
UCEC	All	All	+0.264	.001	6	view →
BLCA	Male	All	+0.377	.021	5	view →
CHOL	All	All	+0.380	.002	3	view →
KIRC	All	All	+0.149	<.001	3	view →
LIHC	All	All	+0.053	.011	3	view →
PRAD	All	All	+1.626	<.001	2	view →
LUAD	All	IV	−0.275	.013	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

PCAT1–COAD

Open the COAD breakdown →