PBX3

Across TCGA patient cohorts, PBX3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,969 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible PBX3-associated proteins across cancer lineages are ZCCHC24, PDLIM3, and TRAP1. Each is linked with PBX3 in more than 5 cancer types. Because this analysis shows association rather than direction, both PBX3-to-partner and partner-to-PBX3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PBX3 versus ZCCHC24 in OV, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PBX3→partner) and Y-score (partner→PBX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ZCCHC24 →	+0.674	+0.645	.005	.008	3	6
OV	PDLIM3 →	+0.809	+0.685	<.001	.001	3	5
OV	TRAP1 →	-0.469	-0.688	.006	.004	3	5
HNSC	CACNA2D1 →	+0.768	+0.741	<.001	<.001	3	5
UCEC	TUBB6 →	+0.483	+0.666	<.001	<.001	3	5
OV	JUP →	-0.622	-0.776	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,969 associations by consensus.

PBX3 vs ZCCHC24 — OV

Explore this scatter interactively →