PBX3

Across TCGA patient cohorts, PBX3 protein abundance is significantly associated with the RNA expression of many other genes, with 2,197 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PBX3-associated genes across cancer lineages are F13A1, SCRN3, and PHOSPHO2. Each is linked with PBX3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PBX3-to-partner and partner-to-PBX3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PBX3 versus F13A1 in GBM, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PBX3→partner) and Y-score (partner→PBX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	F13A1 →	+1.796	+0.707	.003	<.001	3	2
UCEC	SCRN3 →	-0.615	-0.331	<.001	.003	3	2
GBM	PHOSPHO2 →	-0.496	-0.555	.001	.001	3	2
PDAC	CNTN4 →	+0.615	+0.659	.002	.003	3	2
LSCC	APBB1 →	+0.697	+0.460	.004	.001	3	2
LSCC	TSPYL5 →	+1.738	+0.584	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,197 associations by consensus.

PBX3 vs F13A1 — GBM

Explore this scatter interactively →