PBX2P1

Across TCGA pan-cancer cohorts, PBX2P1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated PBX2P1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher PBX2P1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated PBX2P1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and HNSC show a favorable association.

KIRC, HNSC, and ESCA are the cancer types where PBX2P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Quartile	III,IV	0.658	0.297	<.001	67	view →
HNSC	DFS	Tertile	II,III,IV	0.750	0.626	.006	36	view →
ESCA	OS	Tertile	II,III,IV	0.652	0.409	.005	35	view →
LUSC	OS	Tertile	II,III,IV	0.734	0.483	<.001	32	view →
UCEC	OS	Quartile	IV	0.728	0.337	.011	24	view →
SKCM	OS	Quartile	III,IV	0.890	0.719	.002	20	view →
UCS	DFS	Median	IV	0.909	0.416	.008	18	view →
DLBC	DFS	Median	All	0.622	1.000	.014	15	view →
ACC	DFS	Tertile	All	0.498	0.785	.002	14	view →
LGG	OS	Quartile	All	0.327	0.591	.001	14	view →
OV	OS	Quartile	IV	0.589	0.277	.007	12	view →
THYM	DFS	Quartile	II,III,IV	0.902	0.296	.025	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

PBX2P1–KIRC (DFS)

Open the KIRC breakdown →