PBLD

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PBLD RNA expression is significantly associated with the protein abundance of many other proteins, with 15,851 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PBLD-associated proteins across cancer lineages are ASNS, CAD, and EEF2. Each is linked with PBLD in more than 5 cancer types. Because this analysis shows association rather than direction, both PBLD-to-partner and partner-to-PBLD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PBLD versus ASNS in BRCA, with a Pearson correlation of -0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PBLD→partner) and Y-score (partner→PBLD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAASNS →-0.997-0.876<.001<.00136
LUADCAD →-0.278-0.731<.001<.00136
BRCAEEF2 →-0.229-0.716<.001<.00135
BRCANAT10 →-0.315-0.451<.001<.00135
LUADNCL_S67 →-0.954-0.662<.001<.00135
BRCANUDT1 →-0.352-0.658<.001.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,851 associations by consensus.

PBLD vs ASNS — BRCA

Per-sample scatter of PBLD vs ASNS in BRCA (Pearson r = -0.41).

Explore this scatter interactively →

Exploration