PBLD

Across TCGA cell cohorts, PBLD RNA expression is significantly associated with the go_rna of many other GO terms, with 4,419 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PBLD-associated GO terms across cancer lineages are Macroautophagy, Flagellated sperm motility, and Golgi vesicle transport. Each is linked with PBLD in more than 11 cancer types. Because this analysis shows association rather than direction, both PBLD-to-partner and partner-to-PBLD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macroautophagy grouped by PBLD-low versus PBLD-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PBLD→partner) and Y-score (partner→PBLD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Macroautophagy →	+0.061	+1.212	.001	<.001	2	12
BONE	Flagellated sperm motility →	-0.111	-0.988	<.001	<.001	3	11
BREAST	Golgi vesicle transport →	+0.063	+0.867	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.101	-0.805	<.001	<.001	3	11
BONE	Sperm motility →	-0.111	-0.988	<.001	<.001	3	11
BREAST	Transport along microtubule →	+0.042	+0.729	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,419 associations by consensus.

Macroautophagy by PBLD expression — BLOOD_Myeloma

Explore this box plot interactively →