PBDC1

Across TCGA cell cohorts, PBDC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,828 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible PBDC1-associated GO terms across cancer lineages are Nuclear histone mRNA catabolic process, 'de novo' cotranslational protein folding, and 'de novo' protein folding. Each is linked with PBDC1 in more than 9 cancer types. Because this analysis shows association rather than direction, both PBDC1-to-partner and partner-to-PBDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear histone mRNA catabolic process grouped by PBDC1-low versus PBDC1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PBDC1→partner) and Y-score (partner→PBDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Nuclear histone mRNA catabolic process →	+0.115	+0.865	<.001	.001	3	10
BREAST	'de novo' cotranslational protein folding →	+0.171	+0.780	<.001	.005	2	8
BREAST	'de novo' protein folding →	+0.155	+0.983	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Positive regulation of rRNA processing →	+0.110	+0.787	.001	.002	3	6
BLOOD_Leukemia	Positive regulation of mitochondrial translation →	+0.058	+0.728	<.001	<.001	3	6
BLOOD_Leukemia	Histone mRNA metabolic process →	+0.053	+0.712	<.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,828 associations by consensus.

Nuclear histone mRNA catabolic process by PBDC1 expression — OVARY

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