PAXBP1P1

Across TCGA patient cohorts, PAXBP1P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,595 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PAXBP1P1-associated GO terms across cancer lineages are TOR signaling, RNA modification, and Positive regulation of NF-kappaB transcription factor activity. Each is linked with PAXBP1P1 in more than 3 cancer types. Because this analysis shows association rather than direction, both PAXBP1P1-to-partner and partner-to-PAXBP1P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TOR signaling grouped by PAXBP1P1-low versus PAXBP1P1-high in UCEC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PAXBP1P1→partner) and Y-score (partner→PAXBP1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TOR signaling →	+0.159	+0.019	<.001	.003	3	4
STAD	RNA modification →	+0.137	+0.030	<.001	.003	3	4
UCEC	Positive regulation of NF-kappaB transcription factor activity →	+0.105	+0.024	<.001	<.001	3	3
UCEC	Negative regulation of cytoskeleton organization →	+0.125	+0.014	<.001	.003	3	3
STAD	Actin filament bundle organization →	+0.130	+0.019	<.001	.007	3	3
STAD	Regulation of protein serine/threonine kinase activity →	+0.116	+0.034	<.001	.005	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,595 associations by consensus.

TOR signaling by PAXBP1P1 expression — UCEC

Explore this box plot interactively →