PAXBP1-AS1

Across TCGA pan-cancer cohorts, PAXBP1-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated PAXBP1-AS1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher PAXBP1-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated PAXBP1-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCS show a favorable association.

HNSC, UCS, and PAAD are the cancer types where PAXBP1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	0.852	0.720	.002	73	view →
UCS	DFS	Median	II,III,IV	0.552	0.174	<.001	68	view →
PAAD	DFS	Median	All	0.377	0.193	<.001	43	view →
LGG	OS	Tertile	All	0.586	0.402	.001	37	view →
ACC	DFS	Tertile	All	0.324	0.765	<.001	28	view →
SKCM	OS	Tertile	III,IV	0.585	0.266	.002	23	view →
UCEC	OS	Tertile	All	0.912	0.958	.011	22	view →
LIHC	DFS	Quartile	All	0.450	0.619	.003	13	view →
MESO	DFS	Median	IV	0.192	0.466	.006	12	view →
KICH	OS	Tertile	All	0.668	1.000	.018	12	view →
KIRC	OS	Median	All	0.897	0.848	.025	11	view →
STAD	DFS	Tertile	IV	0.255	0.740	.023	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

PAXBP1-AS1–HNSC (OS)

Open the HNSC breakdown →