Across TCGA cell cohorts, PAX9 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,311 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PAX9-associated GO terms across cancer lineages are Positive regulation of natural killer cell activation, Coenzyme A metabolic process, and DNA repair-dependent chromatin remodeling. Each is linked with PAX9 in more than 8 cancer types. Because this analysis shows association rather than direction, both PAX9-to-partner and partner-to-PAX9 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PAX9→partner) and Y-score (partner→PAX9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of natural killer cell activation →	-0.307	-1.123	.004	.001	3	8
BREAST	Coenzyme A metabolic process →	+0.071	+1.078	<.001	<.001	3	8
BONE	DNA repair-dependent chromatin remodeling →	+0.114	+1.330	<.001	.003	2	9
BLOOD_Leukemia	Regulation of inner ear receptor cell differentiation →	+0.976	+0.752	<.001	<.001	3	7
LUNG_NSCLC_LUAD	Regulation of natural killer cell differentiation →	-0.230	-0.986	<.001	.001	3	7
URINARY_TRACT	Natural killer cell chemotaxis →	-1.054	-1.407	.004	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,311 associations by consensus.

Exploration

PAX9 survival (RNA) · tumor vs normal (RNA) · all PAX9 data types