Across TCGA cell cohorts, PAX9 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PAX9-associated genes across cancer lineages are PRAMEF18, IAPP, and OR11H1. Each is linked with PAX9 in more than 1 cancer types. Because this analysis shows association rather than direction, both PAX9-to-partner and partner-to-PAX9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PAX9→partner) and Y-score (partner→PAX9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	PRAMEF18 →	+0.004	+4.643	<.001	.005	3	2
BLOOD_Lymphoma	IAPP →	+0.053	+4.927	<.001	.001	3	1
BLOOD_Lymphoma	OR11H1 →	+0.034	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	KRTAP4-4 →	+0.016	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	OR51S1 →	+0.005	+5.247	<.001	.001	3	1
BLOOD_Lymphoma	OR56A4 →	+0.048	+4.927	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

PAX9 survival (RNA) · tumor vs normal (RNA) · all PAX9 data types