Across TCGA cell cohorts, PAX9 mutation is significantly associated with the mutation status of many other genes, with 4,977 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PAX9-associated genes across cancer lineages are FERMT3, ZNF641, and SERPINA1. Each is linked with PAX9 in more than 3 cancer types. Because this analysis shows association rather than direction, both PAX9-to-partner and partner-to-PAX9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PAX9→partner) and Y-score (partner→PAX9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	FERMT3 →	+4.239	+5.053	.007	.007	1	4
SKIN	ZNF641 →	+4.239	+5.053	.007	.007	1	4
SKIN	SERPINA1 →	+4.239	+5.053	.007	.007	1	4
BLOOD_Leukemia	PRDM4 →	+5.321	+5.894	.002	.002	1	4
BLOOD_Leukemia	SNAP91 →	+4.736	+5.560	.003	.003	1	4
LARGE_INTESTINE	BRPF3 →	+3.951	+4.321	<.001	<.001	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,977 associations by consensus.

Exploration

PAX9 survival (RNA) · tumor vs normal (RNA) · all PAX9 data types