PAX7

Across TCGA patient cohorts, PAX7 protein abundance is significantly associated with the RNA expression of many other genes, with 4,839 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PAX7-associated genes across cancer lineages are SMAD7, SLC11A2, and PHACTR1. Each is linked with PAX7 in more than 1 cancer types. Because this analysis shows association rather than direction, both PAX7-to-partner and partner-to-PAX7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PAX7 versus SMAD7 in LUAD, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PAX7→partner) and Y-score (partner→PAX7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SMAD7 →	+0.808	+1.345	<.001	.004	3	1
LUAD	SLC11A2 →	+0.798	+1.320	.002	.004	3	1
LUAD	PHACTR1 →	+0.654	+1.272	.006	.007	3	1
LUAD	KCNIP3 →	+1.164	+2.096	.004	.003	3	1
LUAD	ORC3 →	-0.838	-2.029	.002	.007	3	1
LUAD	DERL1 →	+0.353	+1.339	.007	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,839 associations by consensus.

PAX7 vs SMAD7 — LUAD

Explore this scatter interactively →