PAX7

Across TCGA cell cohorts, PAX7 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,999 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PAX7-associated GO terms across cancer lineages are Ribose phosphate biosynthetic process, Aerobic respiration, and Purine nucleoside triphosphate biosynthetic process. Each is linked with PAX7 in more than 7 cancer types. Because this analysis shows association rather than direction, both PAX7-to-partner and partner-to-PAX7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribose phosphate biosynthetic process grouped by PAX7-low versus PAX7-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PAX7→partner) and Y-score (partner→PAX7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Ribose phosphate biosynthetic process →	+0.080	+3.356	<.001	.002	2	8
OESOPHAGUS	Aerobic respiration →	+0.091	+1.276	<.001	.002	3	6
OESOPHAGUS	Purine nucleoside triphosphate biosynthetic process →	+0.117	+1.360	.002	.006	3	6
OESOPHAGUS	Purine ribonucleoside triphosphate biosynthetic process →	+0.117	+1.360	.002	.006	3	6
BONE	Skeletal muscle satellite cell differentiation →	+2.405	+5.814	<.001	<.001	3	6
BONE	Purine nucleotide biosynthetic process →	+0.089	+4.808	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,999 associations by consensus.

Ribose phosphate biosynthetic process by PAX7 expression — BONE

Explore this box plot interactively →