Across TCGA patient cohorts, PAX5 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,841 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PAX5-associated proteins across cancer lineages are RCSD1, WAS, and PRKCB. Each is linked with PAX5 in more than 8 cancer types. Because this analysis shows association rather than direction, both PAX5-to-partner and partner-to-PAX5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PAX5→partner) and Y-score (partner→PAX5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RCSD1 →	+0.720	+0.569	<.001	<.001	3	8
UCEC	WAS →	+0.656	+0.417	<.001	.001	3	8
BRCA	PRKCB →	+0.767	+0.503	<.001	<.001	3	8
UCEC	CARMIL2_S1381 →	+1.344	+0.482	<.001	<.001	3	8
LSCC	VAV1 →	+0.485	+0.728	<.001	<.001	3	7
LSCC	ARHGAP15 →	+0.598	+0.782	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,841 associations by consensus.

Exploration

PAX5 survival (RNA) · tumor vs normal (RNA) · all PAX5 data types