Across TCGA patient cohorts, PAX5 protein abundance is significantly associated with the protein abundance of many other proteins, with 59 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PAX5-associated proteins across cancer lineages are PACS2_S453, C19orf47_S151, and C2CD2_S475. Each is linked with PAX5 in more than 1 cancer types. Because this analysis shows association rather than direction, both PAX5-to-partner and partner-to-PAX5 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PAX5→partner) and Y-score (partner→PAX5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PACS2_S453 →	-0.527	-0.477	.002	.004	2	1
PDAC	C19orf47_S151 →	+0.621	+2.154	.004	.003	1	1
PDAC	C2CD2_S475 →	-0.385	-0.700	.002	.001	1	1
PDAC	ADD2_S532 →	+2.351	+2.101	.009	.005	1	1
PDAC	CAMSAP2_S673 →	-1.484	-0.500	.006	.001	1	1
PDAC	CEP170B_S360 →	-0.533	-0.615	.002	.005	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 59 associations by consensus.

Exploration

PAX5 survival (RNA) · tumor vs normal (RNA) · all PAX5 data types