PAX3

Across TCGA cell cohorts, PAX3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,877 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PAX3-associated GO terms across cancer lineages are Regulation of metaphase plate congression, Positive regulation of mitotic cell cycle phase transition, and Mitotic nuclear division. Each is linked with PAX3 in more than 5 cancer types. Because this analysis shows association rather than direction, both PAX3-to-partner and partner-to-PAX3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of metaphase plate congression grouped by PAX3-low versus PAX3-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PAX3→partner) and Y-score (partner→PAX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Regulation of metaphase plate congression →	+0.124	+2.082	.002	<.001	3	5
SOFT_TISSUE	Positive regulation of mitotic cell cycle phase transition →	+0.076	+1.647	.002	<.001	3	5
SOFT_TISSUE	Mitotic nuclear division →	+0.066	+1.561	.001	.001	3	5
SOFT_TISSUE	Nuclear chromosome segregation →	+0.085	+1.678	<.001	.001	3	5
UPPER_AERODIGESTIVE_TRACT	Cardiac muscle cell action potential →	-0.166	-1.009	.001	.005	2	6
SOFT_TISSUE	Potassium ion transport →	-0.036	-1.672	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,877 associations by consensus.

Regulation of metaphase plate congression by PAX3 expression — SKIN

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