PASK

Across TCGA patient cohorts, PASK RNA expression is significantly associated with the protein abundance of many other proteins, with 14,700 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PASK-associated proteins across cancer lineages are LIG1, XAB2, and THRAP3. Each is linked with PASK in more than 7 cancer types. Because this analysis shows association rather than direction, both PASK-to-partner and partner-to-PASK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PASK versus LIG1 in GBM, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PASK→partner) and Y-score (partner→PASK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LIG1 →	+0.579	+0.722	<.001	.001	3	8
BRCA	XAB2 →	+0.238	+0.588	<.001	<.001	3	7
GBM	THRAP3 →	+0.206	+0.381	<.001	.005	3	7
LUAD	MSH6 →	+0.521	+0.541	<.001	<.001	3	7
LUAD	MCM5 →	+0.866	+0.479	<.001	<.001	3	7
GBM	RCC2 →	+0.486	+0.723	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,700 associations by consensus.

PASK vs LIG1 — GBM

Explore this scatter interactively →