PASK

Across TCGA patient cohorts, PASK protein abundance is significantly associated with the RNA expression of many other genes, with 3,208 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PASK-associated genes across cancer lineages are SLCO5A1, RAD51AP1, and PTTG1. Each is linked with PASK in more than 2 cancer types. Because this analysis shows association rather than direction, both PASK-to-partner and partner-to-PASK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PASK versus SLCO5A1 in LSCC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PASK→partner) and Y-score (partner→PASK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SLCO5A1 →	+0.596	+0.338	.006	.003	3	3
LSCC	RAD51AP1 →	+0.752	+0.257	.001	.007	3	3
UCEC	PTTG1 →	+0.936	+0.233	.002	.002	3	3
OV	ETNK1 →	+0.415	+0.369	.007	<.001	3	2
OV	NUPR2 →	-1.390	-0.455	.004	<.001	3	2
BRCA	CSF2RB →	+0.650	+0.211	.006	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,208 associations by consensus.

PASK vs SLCO5A1 — LSCC

Explore this scatter interactively →