PASK

Across TCGA patient cohorts, PASK protein abundance is significantly associated with the protein abundance of many other proteins, with 9,963 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PASK-associated proteins across cancer lineages are HAUS1, HAUS2, and MARCKSL1_S22. Each is linked with PASK in more than 4 cancer types. Because this analysis shows association rather than direction, both PASK-to-partner and partner-to-PASK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PASK versus HAUS1 in OV, with a Pearson correlation of 0.46.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PASK→partner) and Y-score (partner→PASK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HAUS1 →	+0.410	+0.532	<.001	.003	2	5
BRCA	HAUS2 →	+0.333	+0.263	.005	.006	2	5
LUAD	MARCKSL1_S22 →	+1.257	+0.290	<.001	<.001	3	3
LUAD	SUOX →	-0.456	-0.348	<.001	<.001	3	3
OV	PRR11_S40 →	+1.218	+0.741	<.001	<.001	3	3
UCEC	LMNA →	-0.406	-0.222	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,963 associations by consensus.

PASK vs HAUS1 — OV

Explore this scatter interactively →