PASK

Across TCGA cell cohorts, PASK RNA expression is significantly associated with the go_rna of many other GO terms, with 5,315 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PASK-associated GO terms across cancer lineages are Replication fork processing, Double-strand break repair, and Recombinational repair. Each is linked with PASK in more than 19 cancer types. Because this analysis shows association rather than direction, both PASK-to-partner and partner-to-PASK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Replication fork processing grouped by PASK-low versus PASK-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PASK→partner) and Y-score (partner→PASK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Replication fork processing →	+0.153	+2.303	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair →	+0.100	+1.345	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Recombinational repair →	+0.104	+1.340	<.001	<.001	3	18
BONE	DNA-templated DNA replication maintenance of fidelity →	+0.151	+2.175	<.001	<.001	3	18
SOFT_TISSUE	DNA strand elongation involved in DNA replication →	+0.194	+1.631	<.001	<.001	3	18
PANCREAS	Leading strand elongation →	+0.183	+1.276	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,315 associations by consensus.

Replication fork processing by PASK expression — BONE

Explore this box plot interactively →