PASD1

Across TCGA cell cohorts, PASD1 mutation is significantly associated with the RNA expression of many other genes, with 280 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PASD1-associated genes across cancer lineages are OR2T3, OR2L3, and C7. Each is linked with PASD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PASD1-to-partner and partner-to-PASD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2T3 grouped by PASD1-low versus PASD1-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PASD1→partner) and Y-score (partner→PASD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	OR2T3 →	+0.033	+4.672	<.001	.002	3	1
BREAST	OR2L3 →	+0.024	+4.672	<.001	.002	3	1
LUNG_SCLC	C7 →	+1.330	+3.621	<.001	.005	3	1
LUNG_SCLC	HSFY1 →	+0.088	+3.232	.004	.008	3	1
LUNG_SCLC	GSTT4 →	+0.008	+3.684	.004	.001	3	1
LUNG_SCLC	OR13C5 →	+0.037	+4.232	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 280 associations by consensus.

OR2T3 by PASD1 expression — BREAST

Explore this box plot interactively →