PARVG

Across TCGA patient cohorts, PARVG protein abundance is significantly associated with the RNA expression of many other genes, with 20,883 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PARVG-associated genes across cancer lineages are CYTH4, CSF2RB, and HCK. Each is linked with PARVG in more than 9 cancer types. Because this analysis shows association rather than direction, both PARVG-to-partner and partner-to-PARVG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PARVG versus CYTH4 in GBM, with a Pearson correlation of 0.88.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PARVG→partner) and Y-score (partner→PARVG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CYTH4 →	+1.219	+0.834	<.001	<.001	3	10
GBM	CSF2RB →	+1.206	+0.876	<.001	<.001	3	10
GBM	HCK →	+1.272	+0.862	<.001	<.001	3	10
GBM	TLR8 →	+1.175	+0.723	<.001	<.001	3	10
OV	TNFSF13B →	+1.431	+0.590	<.001	<.001	3	10
BRCA	IL4I1 →	+1.459	+0.470	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,883 associations by consensus.

PARVG vs CYTH4 — GBM

Explore this scatter interactively →