PARVG

Across TCGA cell cohorts, PARVG RNA expression is significantly associated with the go_rna of many other GO terms, with 1,897 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PARVG-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Vesicle-mediated transport to the plasma membrane, and Positive regulation of L-glutamate import across plasma membrane. Each is linked with PARVG in more than 5 cancer types. Because this analysis shows association rather than direction, both PARVG-to-partner and partner-to-PARVG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by PARVG-low versus PARVG-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PARVG→partner) and Y-score (partner→PARVG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.148	+0.099	<.001	.008	2	6
OESOPHAGUS	Vesicle-mediated transport to the plasma membrane →	+0.069	+0.105	<.001	.006	2	6
OVARY	Positive regulation of L-glutamate import across plasma membrane →	+0.034	+1.114	.002	.001	3	5
OVARY	Positive regulation of viral process →	+0.068	+1.113	<.001	<.001	3	5
STOMACH	Regulation of translational initiation →	+0.070	+0.160	.006	.005	2	6
OVARY	Establishment of protein localization to endoplasmic reticulum →	+0.064	+0.972	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,897 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by PARVG expression — OESOPHAGUS

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