Across TCGA patient cohorts, PARVA protein abundance is significantly associated with the RNA expression of many other genes, with 18,752 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PARVA-associated genes across cancer lineages are MYL9, SRPX, and SYDE1. Each is linked with PARVA in more than 9 cancer types. Because this analysis shows association rather than direction, both PARVA-to-partner and partner-to-PARVA results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PARVA→partner) and Y-score (partner→PARVA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MYL9 →	+1.359	+0.576	<.001	<.001	3	10
BRCA	SRPX →	+1.580	+0.529	<.001	<.001	3	10
BRCA	SYDE1 →	+0.724	+0.428	<.001	<.001	3	10
BRCA	CALD1 →	+1.296	+0.595	<.001	<.001	3	10
UCEC	CNN1 →	+2.742	+0.775	<.001	<.001	3	10
BRCA	TPM1 →	+0.900	+0.462	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,752 associations by consensus.

Exploration

PARVA survival (RNA) · tumor vs normal (RNA) · all PARVA data types