Across TCGA patient cohorts, PARVA mutation is significantly associated with the RNA expression of many other genes, with 2,065 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PARVA-associated genes across cancer lineages are RPS29P32, OR7E97P, and KRTAP19-1. Each is linked with PARVA in more than 1 cancer types. Because this analysis shows association rather than direction, both PARVA-to-partner and partner-to-PARVA results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PARVA→partner) and Y-score (partner→PARVA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RPS29P32 →	+0.852	+5.631	<.001	.004	3	2
LUAD	OR7E97P →	+0.068	+6.912	<.001	<.001	3	2
LUAD	KRTAP19-1 →	+0.265	+5.217	<.001	.007	3	2
LUSC	CDY8P →	+0.029	+7.924	<.001	.008	3	2
COAD	RNU6-1246P →	+1.377	+7.741	<.001	.009	3	2
COAD	RNU6-521P →	+0.782	+7.741	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,065 associations by consensus.

Exploration

PARVA survival (RNA) · tumor vs normal (RNA) · all PARVA data types