Across TCGA cell cohorts, PARVA RNA expression is significantly associated with the go_rna of many other GO terms, with 5,275 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PARVA-associated GO terms across cancer lineages are Establishment or maintenance of cell polarity regulating cell shape, Regulation of protein K48-linked ubiquitination, and Regulation of cell-substrate junction organization. Each is linked with PARVA in more than 14 cancer types. Because this analysis shows association rather than direction, both PARVA-to-partner and partner-to-PARVA results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PARVA→partner) and Y-score (partner→PARVA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Establishment or maintenance of cell polarity regulating cell shape →	+0.347	+2.219	.007	<.001	3	15
LUNG_NSCLC_LUSC	Regulation of protein K48-linked ubiquitination →	+0.146	+2.581	.001	<.001	3	14
BONE	Regulation of cell-substrate junction organization →	+0.163	+2.021	<.001	<.001	3	13
BONE	Regulation of cell-matrix adhesion →	+0.157	+1.710	<.001	<.001	3	13
BONE	Negative regulation of Rho protein signal transduction →	+0.192	+2.011	<.001	<.001	3	13
BONE	Viral life cycle →	+0.137	+2.675	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,275 associations by consensus.

Exploration

PARVA survival (RNA) · tumor vs normal (RNA) · all PARVA data types