Across TCGA cell cohorts, PARVA mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PARVA-associated genes across cancer lineages are GH2, KRTAP17-1, and OR6M1. Each is linked with PARVA in more than 1 cancer types. Because this analysis shows association rather than direction, both PARVA-to-partner and partner-to-PARVA results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PARVA→partner) and Y-score (partner→PARVA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	GH2 →	+0.030	+5.087	<.001	.004	3	1
URINARY_TRACT	KRTAP17-1 →	+0.026	+5.087	<.001	.004	3	1
LARGE_INTESTINE	OR6M1 →	+0.252	+5.415	<.001	.004	3	1
BLOOD_Lymphoma	C1orf87 →	+0.021	+4.867	.008	.009	3	1
BLOOD_Lymphoma	ART5 →	+0.122	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	DYNAP →	+0.102	+4.867	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

PARVA survival (RNA) · tumor vs normal (RNA) · all PARVA data types