PART1

Across TCGA patient cohorts, PART1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PART1-associated genes across cancer lineages are RNU6-839P and USP9YP2. Each is linked with PART1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PART1-to-partner and partner-to-PART1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-839P grouped by PART1-low versus PART1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PART1→partner) and Y-score (partner→PART1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-839P →	+0.375	+8.066	<.001	.007	3	1
UCEC	USP9YP2 →	+0.054	+8.066	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

RNU6-839P by PART1 expression — UCEC

Explore this box plot interactively →