PARP4

Across TCGA patient cohorts, PARP4 protein abundance is significantly associated with the RNA expression of many other genes, with 21,309 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PARP4-associated genes across cancer lineages are CCNB1IP1, MVP, and FANCE. Each is linked with PARP4 in more than 7 cancer types. Because this analysis shows association rather than direction, both PARP4-to-partner and partner-to-PARP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PARP4 versus CCNB1IP1 in OV, with a Pearson correlation of -0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PARP4→partner) and Y-score (partner→PARP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CCNB1IP1 →	-0.733	-0.324	<.001	.001	3	8
UCEC	MVP →	+1.164	+0.484	.001	<.001	3	8
LSCC	FANCE →	-0.875	-0.368	<.001	<.001	3	7
LSCC	PDZK1IP1 →	+1.575	+0.387	<.001	<.001	3	7
GBM	CDC25A →	-0.892	-0.438	<.001	<.001	3	7
HNSC	ZNF286A →	-0.659	-0.403	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,309 associations by consensus.

PARP4 vs CCNB1IP1 — OV

Explore this scatter interactively →