PARP3

Across TCGA patient cohorts, PARP3 protein abundance is significantly associated with the RNA expression of many other genes, with 11,830 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PARP3-associated genes across cancer lineages are RPAIN, ACMSD, and PLD6. Each is linked with PARP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PARP3-to-partner and partner-to-PARP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PARP3 versus RPAIN in LSCC, with a Pearson correlation of -0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PARP3→partner) and Y-score (partner→PARP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RPAIN →	-0.628	-0.682	.001	.001	3	2
LUAD	ACMSD →	-1.007	-0.614	<.001	.003	3	2
LUAD	PLD6 →	-0.736	-0.738	<.001	<.001	3	2
GBM	BTF3L4P2 →	-0.829	-0.868	<.001	.002	3	2
LUAD	FTH1P25 →	-0.639	-0.769	<.001	<.001	3	2
LSCC	LRRC37BP1 →	-0.548	-0.495	.004	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,830 associations by consensus.

PARP3 vs RPAIN — LSCC

Explore this scatter interactively →