PARP16

Across TCGA patient cohorts, PARP16 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,982 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PARP16-associated proteins across cancer lineages are FAM98B, VEZF1, and GTF2I. Each is linked with PARP16 in more than 4 cancer types. Because this analysis shows association rather than direction, both PARP16-to-partner and partner-to-PARP16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PARP16 versus FAM98B in LSCC, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PARP16→partner) and Y-score (partner→PARP16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FAM98B →	+0.243	+0.301	<.001	<.001	3	5
GBM	VEZF1 →	+0.465	+0.395	<.001	<.001	3	5
LSCC	GTF2I →	+0.419	+0.523	<.001	<.001	3	5
GBM	PNN_S413 →	+0.443	+0.467	<.001	<.001	3	4
OV	PTPN9 →	+0.252	+0.599	<.001	<.001	3	4
HNSC	MYEF2 →	+0.845	+0.615	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,982 associations by consensus.

PARP16 vs FAM98B — LSCC

Explore this scatter interactively →