PARP16

Across TCGA patient cohorts, PARP16 protein abundance is significantly associated with the RNA expression of many other genes, with 5,523 significant associations in total. OV shows the largest number of these associations.

The most reproducible PARP16-associated genes across cancer lineages are WHAMM, NCOA4P3, and FERMT2. Each is linked with PARP16 in more than 2 cancer types. Because this analysis shows association rather than direction, both PARP16-to-partner and partner-to-PARP16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PARP16 versus WHAMM in OV, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PARP16→partner) and Y-score (partner→PARP16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	WHAMM →	+0.717	+0.435	<.001	<.001	3	3
OV	NCOA4P3 →	-1.146	-0.344	<.001	.005	3	2
LSCC	FERMT2 →	-0.591	-0.218	.001	<.001	3	2
OV	CSK →	+0.694	+0.357	.002	.001	3	2
LSCC	CALML4 →	+0.183	+0.303	<.001	<.001	3	2
HNSC	MPP1 →	+0.662	+0.294	.004	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,523 associations by consensus.

PARP16 vs WHAMM — OV

Explore this scatter interactively →