PARP12

Across TCGA patient cohorts, PARP12 protein abundance is significantly associated with the RNA expression of many other genes, with 12,745 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PARP12-associated genes across cancer lineages are OAS2, STAT1, and XAF1. Each is linked with PARP12 in more than 9 cancer types. Because this analysis shows association rather than direction, both PARP12-to-partner and partner-to-PARP12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PARP12 versus OAS2 in OV, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PARP12→partner) and Y-score (partner→PARP12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	OAS2 →	+1.799	+0.378	<.001	<.001	3	10
OV	STAT1 →	+1.219	+0.341	<.001	<.001	3	10
OV	XAF1 →	+1.223	+0.360	<.001	<.001	3	10
OV	EPSTI1 →	+1.459	+0.457	<.001	<.001	3	10
OV	RSAD2 →	+1.895	+0.452	<.001	<.001	3	10
HNSC	OASL →	+2.385	+0.477	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,745 associations by consensus.

PARP12 vs OAS2 — OV

Explore this scatter interactively →