PARP12

Across TCGA patient cohorts, PARP12 protein abundance is significantly associated with the protein abundance of many other proteins, with 21,610 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PARP12-associated proteins across cancer lineages are STAT1, STAT2, and TAP2. Each is linked with PARP12 in more than 9 cancer types. Because this analysis shows association rather than direction, both PARP12-to-partner and partner-to-PARP12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PARP12 versus STAT1 in BRCA, with a Pearson correlation of 0.65.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PARP12→partner) and Y-score (partner→PARP12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	STAT1 →	+0.733	+0.416	<.001	<.001	3	10
OV	STAT2 →	+0.446	+0.353	<.001	.001	3	10
PDAC	TAP2 →	+0.735	+0.247	<.001	<.001	3	10
HNSC	TRIM21 →	+0.530	+0.391	<.001	<.001	3	10
BRCA	PARP14 →	+0.496	+0.396	<.001	<.001	3	10
GBM	PSME2 →	+0.475	+0.416	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,610 associations by consensus.

PARP12 vs STAT1 — BRCA

Explore this scatter interactively →