PARN

Across TCGA patient cohorts, PARN RNA expression is significantly associated with the protein abundance of many other proteins, with 14,363 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PARN-associated proteins across cancer lineages are PARN_S619, LCMT1, and USP7. Each is linked with PARN in more than 6 cancer types. Because this analysis shows association rather than direction, both PARN-to-partner and partner-to-PARN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PARN versus PARN_S619 in OV, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PARN→partner) and Y-score (partner→PARN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PARN_S619 →	+0.830	+0.664	<.001	<.001	3	7
BRCA	LCMT1 →	+0.493	+0.425	<.001	.003	3	5
LSCC	USP7 →	+0.281	+0.506	<.001	<.001	3	5
BRCA	ERCC4 →	+0.277	+0.551	<.001	<.001	3	5
BRCA	THUMPD1 →	+0.318	+0.400	<.001	<.001	3	5
BRCA	MRTFB →	+0.321	+0.375	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,363 associations by consensus.

PARN vs PARN_S619 — OV

Explore this scatter interactively →