PARL

Across TCGA patient cohorts, PARL RNA expression is significantly associated with the protein abundance of many other proteins, with 14,416 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PARL-associated proteins across cancer lineages are PAK2, FXR1, and GMPS. Each is linked with PARL in more than 6 cancer types. Because this analysis shows association rather than direction, both PARL-to-partner and partner-to-PARL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PARL versus PAK2 in OV, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PARL→partner) and Y-score (partner→PARL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PAK2 →	+0.260	+0.540	.001	<.001	3	7
LSCC	FXR1 →	+0.517	+0.957	<.001	<.001	3	7
LSCC	GMPS →	+0.531	+0.788	<.001	<.001	3	7
PDAC	CDCA8_S219 →	+0.825	+0.287	<.001	.002	3	6
LSCC	CHERP →	+0.233	+0.604	<.001	<.001	3	6
HNSC	RFC3 →	+0.264	+0.687	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,416 associations by consensus.

PARL vs PAK2 — OV

Explore this scatter interactively →