Across TCGA patient cohorts, PARG RNA expression is significantly associated with the protein abundance of many other proteins, with 15,868 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PARG-associated proteins across cancer lineages are KIFBP, VPS26A, and DDX50. Each is linked with PARG in more than 5 cancer types. Because this analysis shows association rather than direction, both PARG-to-partner and partner-to-PARG results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PARG→partner) and Y-score (partner→PARG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	KIFBP →	+0.304	+0.317	<.001	<.001	3	6
GBM	VPS26A →	+0.262	+0.374	<.001	<.001	3	6
OV	DDX50 →	+0.375	+0.386	.001	.002	3	6
UCEC	TIAL1 →	+0.184	+0.717	<.001	.004	3	5
LUAD	CCAR1 →	+0.177	+0.410	<.001	<.001	3	5
LUAD	CCDC6_S52 →	+0.714	+0.310	.003	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,868 associations by consensus.

Exploration

PARG survival (RNA) · tumor vs normal (RNA) · all PARG data types