Across TCGA cell cohorts, PARG RNA expression is significantly associated with the go_rna of many other GO terms, with 4,346 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PARG-associated GO terms across cancer lineages are Regulation of sister chromatid cohesion, Lagging strand elongation, and Base-excision repair, gap-filling. Each is linked with PARG in more than 17 cancer types. Because this analysis shows association rather than direction, both PARG-to-partner and partner-to-PARG results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PARG→partner) and Y-score (partner→PARG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of sister chromatid cohesion →	+0.143	+0.894	.001	<.001	3	18
BLOOD_Leukemia	Lagging strand elongation →	+0.097	+0.717	<.001	<.001	3	17
LUNG_NSCLC_LUSC	Base-excision repair, gap-filling →	+0.145	+0.994	<.001	<.001	3	16
BLOOD_Myeloma	Subtelomeric heterochromatin formation →	+0.103	+0.865	<.001	.002	3	16
PANCREAS	Protein localization to chromosome →	+0.097	+0.709	<.001	.002	3	16
SOFT_TISSUE	Nuclear transport →	+0.080	+0.778	<.001	.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,346 associations by consensus.

Exploration

PARG survival (RNA) · tumor vs normal (RNA) · all PARG data types