PARD6G-AS1

Across TCGA pan-cancer cohorts, PARD6G-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated PARD6G-AS1 data layer compared with 2 for mutation status.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher PARD6G-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PARD6G-AS1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and HNSC show a favorable association.

ACC, MESO, and BRCA are the cancer types where PARD6G-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Quartile	All	0.444	0.813	<.001	60	view →
MESO	DFS	Quartile	All	0.279	0.507	.010	41	view →
BRCA	OS	Tertile	III,IV	0.944	0.844	.004	33	view →
BLCA	DFS	Median	All	0.375	0.583	.010	21	view →
THCA	OS	Median	III,IV	0.895	1.000	.002	21	view →
ESCA	OS	Quartile	All	0.293	0.607	.006	19	view →
SKCM	DFS	Quartile	All	0.664	0.835	.004	15	view →
CHOL	DFS	Tertile	II,III,IV	0.171	0.615	.013	14	view →
COAD	DFS	Quartile	All	0.718	0.836	.018	12	view →
HNSC	OS	Quartile	III,IV	0.816	0.651	.005	12	view →
UCEC	OS	Tertile	All	0.692	0.677	.025	12	view →
DLBC	DFS	Median	IV	0.128	1.000	.017	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

PARD6G-AS1–ACC (DFS)

Open the ACC breakdown →