PARD3

Across TCGA patient cohorts, PARD3 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,033 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PARD3-associated proteins across cancer lineages are PARD3_S144, PARD3_S852, and PARD3_S873. Each is linked with PARD3 in more than 6 cancer types. Because this analysis shows association rather than direction, both PARD3-to-partner and partner-to-PARD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PARD3 versus PARD3_S144 in HNSC, with a Pearson correlation of 0.22.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PARD3→partner) and Y-score (partner→PARD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PARD3_S144 →	+0.651	+1.035	<.001	<.001	3	7
LSCC	PARD3_S852 →	+0.861	+0.833	<.001	<.001	3	6
LSCC	PARD3_S873 →	+1.006	+0.745	<.001	<.001	3	5
LSCC	PLCL2 →	-0.364	-0.922	<.001	<.001	3	5
BRCA	CUL2 →	+0.296	+0.737	<.001	<.001	2	6
OV	RTKN →	+0.389	+0.329	.007	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,033 associations by consensus.

PARD3 vs PARD3_S144 — HNSC

Explore this scatter interactively →