PARD3

Across TCGA patient cohorts, PARD3 protein abundance is significantly associated with the RNA expression of many other genes, with 10,932 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PARD3-associated genes across cancer lineages are RPS12P16, CCNY, and RPL37P18. Each is linked with PARD3 in more than 7 cancer types. Because this analysis shows association rather than direction, both PARD3-to-partner and partner-to-PARD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PARD3 versus RPS12P16 in LSCC, with a Pearson correlation of 0.78.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PARD3→partner) and Y-score (partner→PARD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RPS12P16 →	+1.130	+0.527	<.001	<.001	3	8
HNSC	CCNY →	+0.503	+0.269	.007	.003	3	7
LSCC	RPL37P18 →	+1.017	+0.457	<.001	<.001	3	7
LSCC	PARD3-AS1 →	+1.459	+0.559	<.001	<.001	3	6
LSCC	ELOBP4 →	+0.949	+0.455	<.001	<.001	3	6
GBM	WAC-AS1 →	+0.541	+0.373	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,932 associations by consensus.

PARD3 vs RPS12P16 — LSCC

Explore this scatter interactively →